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Clostridium Butyricum Product

5x 10^9 cfu/g Clostridium butyricum supply

Clostridium butyricum is a strictly anaerobic endospore-forming Gram-positive butyric acid–producing bacillus subsisting, it is a common human and animal gut commensal bacterium, act as a probiotic are used as potential alternatives to antibiotics for  non-antimicrobial induced diarrhea, antimicrobial-associated diarrhea, constipation, and irritable bowel syndrome . 

Clostridium butyricum can clostridia produce short-chain fatty acids (SCFAs), primarily butyrate and acetate, by means of fermentation of mainly undigested dietary carbohydrates. Butyrate serves as energy for colonic epithelial cells, plays a key role in maintaining gut immunological homeostasis, and exerts anti-inflammatory effect.

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  • Bacteria count :  5 x 10^9 cfu/g  ,  1 x 10^10 cfu/g

  • Fineness:  60 mesh screen

  • Moisture: 8%

  • 25 g / barrel or  as per customers request

  • Feed Additives

  • Aquaculture

  • Shrimp Farming

  • Fish Farming

  • Broiler Farming

  • Normalizes the intestinal microbiota

  • Modifies the intestinal microbiota by increasing Bifidobacteria and Lactobacilli

  • Increase the abundance of Bacteroidetes and Bifidobacteria in intestinal microbiota

  • Significantly increased the amount of butyrate in the caeca that provides energy to enterocytes, resulting in increased weight gains

  • Enhance immue function and prevent tumor occurrence

  • Reducing the populations of unwanted bacteria

  • Enhanced growth performance 20%~30%

Dosage & Method
  • For aquaculture using,  mix 200 gram for 1 MT feeding or  0.15 ppm for pond spray after dissolved in water.

  • For animal farming,  mix 200 gram for 1 MT feeding or 0.1 ppm dissolved in drinking water.

  • Routine dosing can keep performance.

  • Store in cool, dry location, keep out of direct sunshine and moisture. 

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Antibacterial performance


   (a) Against  E. coli Test            (b) Against Salmonella Test           (c)  Against S. aureus test

Antibiotic resistance research

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          (a) Control  (b) Enramycin 12 ppm    (c) Nosiheptide 25 ppm   (d) Kitasamycin 165 ppm

(e)Bacitracin Zinc 45ppm  (f) Flavomycoin 10 ppm  (g) Chlortetracycline 100 ppm    (h) Quinocetone 323 ppm


1) Clostridium acidophilus should separate use with virginiamycin & Calcium oxytetracycline & Chlortetracycline

2) When Clostridium acidophilus is used together with the following antibiotics, the amount of antibiotics added in the feed should be at the following content:

Enramycin < 12 ppm                  Nosiheptide < 75 ppm                  Kitasamycin< 16.5 ppm               Amiramycin < 40 ppm

Flavomycoin< 10 ppm               Quinocetone < 65 ppm                  Bacitracin Zinc < 45 ppm

Poultry Application Research

Test method:  

Group A 10,000 birds, use clostridium acidophilus when 1-10 days old only,  Group B 5000 birds, use clostridium acidophilus  when 1-10 days old only, Group C 10,000 birds, used clostridium acidophilus throughout, Group D 10,000 birds, without used clostridium acidophilus throughout, monitor data once a week to monitor the casualty rate and fecal residue ratio for comparison




Test Conclusion:  The application of Clostridium butyricum on broilers can significantly increase the feed conversion rate, improve the growth performance of broilers and reduce the mortality rate.

Swine Application Research

Monitor the performance from 80 days of pregnancy to weaning of piglets (28 days old),  Clostridium acidophilus can reduce piglet diarrhea rate and increase survival rate.


270 piglets in the control, 273 piglets in the treated, the test period was 10 days. Clostridium acidophilus can increase daily feed intake and daily weight gain, reduce F/G ratio


Package and Storage


100 g/bag, 250g/bag, 500g/bag, 1kg/bag


20kg/25kg/drum or as requirements


If 25kg/bag, 1,000kg/40bag/pallet


One 20'GP can contain 10-14 tons if bag


Stored 24 months sealed in a cool, dry and airy place. 

Prevent from direct sunlight, heat and dampness


Do not use with disinfectant or antibacterial agents

Products Technical Data




Viable count (CFU/g)

5 billion (5.0x10^9)

10 billion (1.0x10^10)


Light yellow

Light yellow

Recommended dosage

200 g/ton

100 g/ton

Key component

Clostridium Butyricum, Carrier




Slight fermentation odor

Particle size

More than 98% pass through standard sieve of 60 meshes (0.25mm)

Loss on drying


Arsenic (As)

≤2 mg/kg

Plumbum (Pb)

≤5 mg/kg

Mercury (Hg)

≤0.1 mg/kg

Cadmium (Cd)

≤0.5 mg/kg

Microbial contamination rate


Coli group

≤100 CFU/g



Total count of mold

≤2.0x104 CFU/g

Pathogenic bacteria



Product List

Sustainable Soil FertilityNon Residue Crop ProtectionOptimal Growth Management
Animal Husbandry
Feed Probiotics SolutionManure CompostingOdor Management
Waste Management
Waste Water Treatment
Surface Water Treatment
Bacteria supply
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